UC Associate Professor Laurie McKay is a sleep expert, specialising in children who are on the autism spectrum and typically don't naturally produce melatonin as efficiently as other children.
The studys lead author泭Associate Professor Laurie McLay泭says the treatment, which mimics the bodys natural sleep hormone, can make a huge difference for families with children on the autism spectrum.
We know that sleep problems are really common for children on the autism spectrum, with between 50% and 80% of children affected, she says.
A combination of biological, environmental, behavioural and psychological factors contribute towards sleep problems. From a biological perspective, the timing and amount of melatonin produced in children on the spectrum can differ from typically developing children.
Sleep deprivation impacts significantly on these children and their families, coming in on top of other challenges, so we feel it is important to understand how to better support them to get a good nights sleep.泭
Melatonin has been funded by Pharmac since 2017 for children on the autism spectrum who have persistent, pervasive sleep problems. It has no known significant side effects, making it an attractive option for parents. It is effective and easy to administer compared to many other treatments.泭
An effective alternative is behavioural interventions, however these require a lot of effort and time on the part of parents, as well as professional support that is not always available, Dr McLay says. 泭
An expert on behavioural interventions for sleep problems, Dr McLay worked with children on the autism spectrum and their families before joining UC as a lecturer and researcher. She wanted to understand how popular melatonin was in Aotearoa New Zealand, and worked with a team of researchers including UCs Professor Philip Schluter and doctoral student Emma Woodford, Dr Matt Eggleston from the Mental Health Division of the Canterbury District Health Board, and Nick Bowden from the University of Otagos Department of Womens and Childrens Health and A Better Start National Science Challenge.
The team obtained data for 11,202 children on the autism spectrum aged up to 18 years in Aotearoa New Zealand. While the efficacy of melatonin for sleep problems in children on the autism spectrum is well-known, the rate and patterns of melatonin use in New 厙ぴ勛圖was not.
The study, published in泭Sleep Medicine泭in March 2021, found that rates of melatonin dispensing were higher among females, school-aged children and those of European ethnicity. Rates were also higher among those with co-occurring mental health conditions, particularly ADHD. No difference was found in rates of melatonin dispensing for different levels of deprivation and urban/rural locations.
Dr McLay is anticipating a second study will be published later this year, looking at the secondary benefits of improving childrens sleep. 泭Further research is planned to explore how melatonin could be used alongside behavioural interventions to further improve sleep for children on the autism spectrum.
The research does not explore the use of melatonin among children who are not on the autism spectrum.
Dr泭McLay leads the泭Good Nights Programme泭at UC,泭an innovative research programme and cost-free nationwide clinical service that helps children with autism get a better night's sleep.
She will present on the topic of泭Quality Sleep: How can we better support children with Autism?泭At the upcoming泭Child Well-being Research Symposium泭on 8 9 April at UC.
